Pay in installments of $25.00 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Jul 23 - Jul 28
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
SFRP1 Recombinant Rabbit mAb (S-3071-18)Product Specification Host Rabbit Antigen SFRP1 Synonyms Secreted frizzled related protein 1; FRP 1; sFRP 1; Secreted apoptosis related protein 2 (SARP 2); FRP; FRP1; SARP2 Immunogen Synthetic Peptide Location Secreted Accession Q8N474 Clone Number S 3071 18 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P Reactivity Hu Positive Sample A549, SK MEL 28 Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical
Product Specification
| Host | Rabbit |
| Antigen | SFRP1 |
| Synonyms | Secreted frizzled-related protein 1; FRP-1; sFRP-1; Secreted apoptosis-related protein 2 (SARP-2); FRP; FRP1; SARP2 |
| Immunogen | Synthetic Peptide |
| Location | Secreted |
| Accession | Q8N474 |
| Clone Number | S-3071-18 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P |
| Reactivity | Hu |
| Positive Sample | A549, SK-MEL-28 |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Hu |
| IHC-P | 1:200 | Hu |
Background
SFRP1 (Secreted Frizzled-Related Protein 1) is a 313-amino-acid, cysteine-rich antagonist of Wnt signaling that is secreted into the extracellular space where it binds Wnt ligands and Frizzled receptors to modulate β-catenin–dependent and –independent pathways, thereby regulating embryonic segmentation, eye, heart and bone development, as well as adult tissue homeostasis, while its epigenetic or mutational silencing in cancers removes this brake on Wnt signaling and drives tumor progression, invasion and metastasis.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy