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Description
Rat Anti-Mouse CD144 Antibody (S-R719)Product Specification Host Rat Antigen CD144 Synonyms Cadherin 5; Vascular endothelial cadherin (VE cadherin); Cdh5 Location Cytoplasm, Cell membrane, Cell junction Accession P55284 Clone Number S R719 Antibody Type Rat mAb Isotype IgG1,k Application FCM Reactivity Ms Purification Protein G Concentration 2 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS pH7. 4 Stability & Storage 12 months from date of receipt
Product Specification
| Host | Rat |
| Antigen | CD144 |
| Synonyms | Cadherin-5; Vascular endothelial cadherin (VE-cadherin); Cdh5 |
| Location | Cytoplasm, Cell membrane, Cell junction |
| Accession | P55284 |
| Clone Number | S-R719 |
| Antibody Type | Rat mAb |
| Isotype | IgG1,k |
| Application | FCM |
| Reactivity | Ms |
| Purification | Protein G |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 1: | Ms |
Background
CD144, also known as VE-cadherin or cadherin-5, is a calcium-dependent cell–cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail, expressed almost exclusively at the adherens junctions of endothelial cells in blood and lymphatic vessels, where it mediates homophilic adhesion, controls endothelial permeability, maintains vascular integrity, promotes endothelial quiescence and tubulogenesis, and is indispensable for embryonic vascular development since its genetic deletion or truncation causes mid-gestational lethality due to vessel disassembly and hemorrhage.
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