SKU: 62604618845

Phospho-SMAD1 (Ser463/465)/ SMAD5 (Ser463/465)/ SMAD9 (Ser465/467) Recombinant Rabbit mAb (S-3412)

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Description

Phospho-SMAD1 (Ser463/465)/ SMAD5 (Ser463/465)/ SMAD9 (Ser465/467) Recombinant Rabbit mAb (S-3412)Product Specification Host Rabbit Antigen Phospho SMAD1 (Ser463 465) SMAD5 (Ser463 465) SMAD9 (Ser465 467) Synonyms Mothers against decapentaplegic homolog; MAD homolog; Mothers against DPP homolog; SMAD family member Location Cytoplasm, Nucleus, Mitochondrion Accession Q99717Q15797O15198 Clone Number S 3412 Antibody Type Recombinant mAb Isotype IgG Application WB Reactivity Hu, Ms Purification Protein A Concentration 0. 5 mg ml Conjugation

Product Specification


Host Rabbit
Antigen Phospho-SMAD1 (Ser463/465)/ SMAD5 (Ser463/465)/ SMAD9 (Ser465/467)
Synonyms Mothers against decapentaplegic homolog; MAD homolog; Mothers against DPP homolog; SMAD family member
Location Cytoplasm, Nucleus, Mitochondrion
Accession Q99717、Q15797、O15198
Clone Number S-3412
Antibody Type Recombinant mAb
Isotype IgG
Application WB
Reactivity Hu, Ms
Purification Protein A
Concentration 0.5 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


application dilution species
WB 1:1000 Hu, Ms

Background

Phospho-SMAD1 (Ser463/465)/SMAD5 (Ser463/465)/SMAD9 (Ser465/467) proteins are the BMP-activated, C-terminally phosphorylated forms of the R-SMADs 1, 5 and 9 that, upon phosphorylation by activated type-I BMP receptors, form heteromeric complexes with co-SMAD4, translocate into the nucleus and directly bind to BMP-responsive promoter elements to orchestrate transcriptional programs governing cell fate, proliferation, differentiation and apoptosis across developmental and homeostatic contexts.

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SKU: 62604618845

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4.8 ★★★★★
Based on 11 reviews
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Verified Purchase
S. Berg
Natrona Heights, US
★★★★★ 5
Good balls
Color: S6-glow
My dog is a chewer, and these have held up for close to a year actually a pretty good product
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 27, 2026
N
Verified Purchase
nanny america
Natrona Heights, US
★★★★★ 3
Disappointed
Color: S6-muti-color
These were great for about 20 minutes then they stopped squeaking...we have 2 left that I have saved but the other 4 do not squeak anymore...disappointed as my dog loves to squeak things...would not buy these again...My dog is only an 8lb dog too...but he can still play with the balls without the squeak...
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 26, 2026
J
Verified Purchase
joymom
Birmingham, US
★★★★★ 5
Great Value for a ball my dog loves!
Color: S6-muti-color
I wish these ball were in the subscription program! My dog gets sooo excited by the new ball, but her interest in things lasts for a few days. She kills the squeak within 11minutes, but the squeaker stays in place rather than becoming a chocking or swallow hazard, and she still loves to chew it. Next, we must throw the ball approximately 723 times the first day, possibly 496 times on day 2, and just 3- 4 on day 3, at which point she will chase the ball before hollering "it's over here if you need it," while she checks on the chipmunk den. We currently have 17 of these balls in our yard (because we have given several leftovers to a less discriminating doodle next door). These balls hold up really well, get her extremely active for the first couple of days, and are a much cheaper than doggie daycare (after an active morning with a new ball, she is happy to chew on it and sleep much of the day). I always have these on hand!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on November 22, 2025
M
Verified Purchase
Michelle
Port Orchard, US
★★★★★ 4
Pieces chewed off
Color: white & green
My Aussiedoodle loves it. I throw it down the hallway, it bounces crazy, and he chases it. The only complaint is that he can't chew much of the ball part. So now I have to have it put away and brought out for special playtime.
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Reviewed in the United States on April 9, 2026
R
Ryan
Alexandria, US
★★★★★ 5
Solid interactive automatic vibrating dog ball toy
Color: Blue, Color: Blue
Picked up this ITEHZTO interactive automatic vibrating dog ball for our pup and it’s a fun, engaging toy that keeps her entertained. It’s rechargeable with USB, motion-activated, and has a good vibrating/rolling action that gets her chasing and playing on her own. The durable build seems like it can handle some rough play, and it’s a nice size for indoor or outdoor use. It lights up or vibrates when activated which adds extra excitement, especially during evening playtime. Battery life is decent and recharges quickly. Great for when she needs mental and physical stimulation without me having to throw a ball constantly. Overall a solid interactive dog toy that does a great job keeping active dogs busy. Good value if your dog loves chasing moving/vibrating toys!
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Reviewed in the United States on April 30, 2026

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