SKU: 9604941272

Human ABP1/AOC1 Protein, His Tag

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Description

Human ABP1/AOC1 Protein, His TagProduct Specification Species Human Synonyms Diamine oxidase [copper containing], Amiloride binding protein, Amiloride binding protein 1, Amine oxidase copper domain containing protein 1, Histaminase, Kidney amine oxidase (KAO; KDAO), ABP, DAO Accession P19801 Amino Acid Sequence Protein sequence (P19801, Glu20 Val751, with C His Tag)

Product Specification


Species Human
Synonyms Diamine oxidase [copper-containing], Amiloride-binding protein, Amiloride-binding protein 1, Amine oxidase copper domain-containing protein 1, Histaminase, Kidney amine oxidase (KAO; KDAO), ABP, DAO
Accession P19801
Amino Acid Sequence

Protein sequence (P19801, Glu20-Val751, with C-His Tag) EPSPGTLPRKAGVFSDLSNQELKAVHSFLWSKKELRLQPSSTTTMAKNTVFLIEMLLPKKYHVLRFLDKGERHPVREARAVIFFGDQEHPNVTEFAVGPLPGPCYMRALSPRPGYQSSWASRPISTAEYALLYHTLQEATKPLHQFFLNTTGFSFQDCHDRCLAFTDVAPRGVASGQRRSWLIIQRYVEGYFLHPTGLELLVDHGSTDAGHWAVEQVWYNGKFYGSPEELARKYADGEVDVVVLEDPLPGGKGHDSTEEPPLFSSHKPRGDFPSPIHVSGPRLVQPHGPRFRLEGNAVLYGGWSFAFRLRSSSGLQVLNVHFGGERIAYEVSVQEAVALYGGHTPAGMQTKYLDVGWGLGSVTHELAPGIDCPETATFLDTFHYYDADDPVHYPRALCLFEMPTGVPLRRHFNSNFKGGFNFYAGLKGQVLVLRTTSTVYNYDYIWDFIFYPNGVMEAKMHATGYVHATFYTPEGLRHGTRLHTHLIGNIHTHLVHYRVDLDVAGTKNSFQTLQMKLENITNPWSPRHRVVQPTLEQTQYSWERQAAFRFKRKLPKYLLFTSPQENPWGHKRTYRLQIHSMADQVLPPGWQEEQAITWARYPLAVTKYRESELCSSSIYHQNDPWHPPVVFEQFLHNNENIENEDLVAWVTVGFLHIPHSEDIPNTATPGNSVGFLLRPFNFFPEDPSLASRDTVIVWPRDNGPNYVQRWIPEDRDCSMPPPFSYNGTYRPV

Expression System HEK293
Molecular Weight Predicted MW: 85.1 kDa Observed MW: 95 kDa
Purity >95% by SDS-PAGE
Endotoxin <1EU/μg
Conjugation Unconjugated
Physical Appearance Lyophilized powder
Storage Buffer

Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4 with 3% trehalose.

Reconstitution Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.
Stability & Storage

12 months from date of receipt, -20 to -70 °C as supplied.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
1 week, 2 to 8 °C under sterile conditions after reconstitution.
Please avoid repeated freeze-thaw cycles.

Background

AOC1, or Amine Oxidase Copper Containing 1, is a key enzyme in histamine and polyamine metabolism. Primarily expressed in the intestine, placenta, and kidney, it catalyzes the degradation of histamine and oxidative deamination of polyamines like putrescine. This function is crucial for regulating local histamine levels, thereby influencing inflammatory and immune responses. AOC1 also plays a significant role in intestinal barrier function and mucosal protection. Its activity impacts various physiological and pathological processes, including allergies, asthma, and inflammatory bowel disease. Furthermore, AOC1 is a target for certain anti-inflammatory drugs, highlighting its therapeutic relevance. Genetic variations in AOC1 can affect enzyme activity and individual susceptibility to related disorders.

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SKU: 9604941272

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4.3 ★★★★★
Based on 26 reviews
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C
Verified Purchase
CJHenry
Bozeman, US
★★★★★ 5
Silky and Soothing
Color: Cream, Size: 2 Pack Queen(20"X 30")
I thought I was getting 1 of the queen sized but I got 2. I got these for my Pomeranian's fuzzy pillow. He's always hot and these are very cooling and very good quality. He loves them and are very comfortable for him. They totally transformed his shaggy old pillow. I used the larger body pillow covers to replace the covers I had. They matched my bedspread perfectly. I use 2 body pillows along the exterior wall in my bedroom where there is cold coming through the floor in the winter. I'm sure I will enjoy them in the summer when it's hot too!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on January 10, 2026
N
Verified Purchase
Nicole Hoelting
Birmingham, US
★★★★★ 5
Finally sleeping through the night without waking up drenched
I was dealing with night sweats almost every night. Waking up overheated, flipping my pillow over constantly, just uncomfortable and restless. It was starting to mess with my sleep in a real way. Since switching to this cooling pillowcase (and pairing it with a cooling blanket), it’s been a completely different experience. I’m actually staying cool through the night and not waking up soaked or irritated. The fabric feels cool to the touch right away and doesn’t trap heat like a regular pillowcase. It’s smooth, comfortable, and still feels good after washing. Not stiff or weird like some “cooling” materials can be. Is it magic? No. But does it noticeably reduce overheating and help you sleep better? Absolutely. If you run hot at night or deal with night sweats, this is one of those small upgrades that makes a big difference. I wish I had bought it sooner.
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Reviewed in the United States on March 19, 2026
A
Verified Purchase
Amazing Sally
Cuba, US
★★★★★ 5
so far so good
I was surprised at this pair of pillow cases only because the material seemed impossible to be cooling - it's that weird polyester blend. So far I have not awoken feeling sweaty around my face and scalp. I don't recall what I originally paid but I think it is great value for money! If you are sensitive to out of the box smell, I washed mine first and it didn't impede on the efficacy of the cooling!
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Reviewed in the United States on April 28, 2026
D
Verified Purchase
Devin Hill
Chelsea, US
★★★★★ 5
It’s like sleeping on a beach in San Vito lo Capo
Italian voice: I’m a big meaty fella so I put off a lot of heat ya hear. These pillow cases have changed my life. One moment they’re hot and the next you flip them and you’re blasted with a blast of ice cool what it feels like to chew 5 gum feeling capeesh. I would reccomend these pillow cases to even my grandma. If ya wanta get a rest so good that it feels like ya been sleeping with the fishes get these pillow cases, they’re the real deal. Then stop at Pauline’s joint and grab a slice of pizza say Vinnie sent ya. Anyways I gotta go my wife’s cooking up a mean lasgna and we’re gonna watch the dodgers. Let me know how these treat ya I guarantee they will change your life. Vinnie out
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Reviewed in the United States on February 15, 2026
A
Verified Purchase
Amazon Customer
Omaha, US
★★★★★ 4
Soft "cooling" case.
Yes it is very cool when you lay on it. It doesn't stay cold though. Within a minute or 2 to whatever your temp is.
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Reviewed in the United States on December 25, 2025

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