SKU: 51744310902

YK-11 Poeder, 1gr

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YK-11 Poeder, 1grYK 11 Wat is YK 11? YK 11, ook bekend als myostine, is een selectieve androgeenreceptormodulator (SARM) die klinisch is aangetoond de androgeenreceptor gedeeltelijk te activeren en tegelijkertijd te functioneren als een myostatineremmer. Onderzoek en eigenschappen Een studie van Lee et al. onderzocht YK 11 als een potentieel middel voor spieropbouw en spierbehoud in situaties van sepsis. In het onderzoek kregen muizen tien dagen lang twee

YK-11

Wat is YK-11?

YK-11, ook bekend als myostine, is een selectieve androgeenreceptormodulator (SARM) die klinisch is aangetoond de androgeenreceptor gedeeltelijk te activeren en tegelijkertijd te functioneren als een myostatineremmer.

Onderzoek en eigenschappen

Een studie van Lee et al. onderzocht YK-11 als een potentieel middel voor spieropbouw en spierbehoud in situaties van sepsis. In het onderzoek kregen muizen tien dagen lang twee verschillende doses YK-11 toegediend (oraal, 350 mg/kg en 700 mg/kg), waarna ze blootgesteld werden aan een peritoneale injectie van E. coli-bacteriën.

Het onderzoek toonde aan dat YK-11 de werking van myostatine remt — een hormoon dat spiergroei beperkt (bron). Behandelde muizen behielden hun lichaamsmassa tijdens ziekte en hadden een gunstigere vet-spierverhouding ten opzichte van de controlegroep.

Na blootstelling aan systemische E. coli konden de behandelde muizen spiermassa in rug en dijen beter herstellen. Hun spiercellen waren bovendien beter bestand tegen atrofie.

Effecten op immuunrespons en organen

Naast effecten op spiermassa, had YK-11 ook impact op de immuunreactie. Behandeling resulteerde in een verlaging van endotoxines en ontstekingsmarkers in de longen. Ook biomarkers voor orgaanschade — zoals AST, ALT en BUN — waren verlaagd.

De eliminatie van schadelijke bacteriën uit organen werd verbeterd bij muizen die met YK-11 waren behandeld (bron), en het overlevingspercentage na sepsis bleek hoger tot aan het 72-uurmerk.

🧪 Inhoud

Het potje bevat 1 gram puur YK-11 poeder.
Een maatschep is niet inbegrepen.
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📄 Disclaimer

Dit materiaal wordt uitsluitend verkocht voor gebruik in laboratoriumonderzoek. Verkoopvoorwaarden zijn van toepassing. Niet voor menselijke consumptie, noch voor medisch, diergeneeskundig of huishoudelijk gebruik. Maak uzelf vertrouwd met onze DISCLAIMER voordat u bestelt.

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SKU: 51744310902

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Joy A. Rector
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Helped my class so much with fostering relationships
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This is a really great study bible especially if you are looking for a first time study bible it has lots of pages and is kind of heavy I used to be KJV only but have come to love the NKJV because its almost exactly like the KJV except it takes out the way they talked when KJV was releasedit doesnt include thee thou and words like sayeth instead has a lot of word you and better to understand. It is filled with God's love and grace and will help you to understand God's love and grace and also to study the bible. I got out of living a fear based relationship with God and living by works and having religious perfectionism this study bible has helped to reinforce the work of God's love and will help you if you read the bible and feel condemned or are struggling to understand. It's got great notes a big section rather than few which i didnt like that many study bibles dont have enough notes this has extra parts to help you to understand and also included prayers and has a good outline of yhe original text that is very well to read rather than making you feel overwhelmed. If you are looking for your first time study bible or are considering buying this I would reccomend it, don't be thrown off by the title of the study bible. Godbless.
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I can't put this bible down!
What a perfect size. The font is totally readable and enhances the experience (way to go 2K/Denmark). The layout is an invitation to read: simple bible text with little to no distractions. References on the sides of the page are a great idea. All the references you might desire are there but they're out of the way - they don't interfere with your ability to pay attention to the bible text. The slightly cream toned white paper is sublime: wonderfully opaque and easy to page turn. The line matched text solves ghosting issues you've doubtlessly hated in previous bibles. I LOVE the red text (not words of Christ in red, this is a black letter edition) - it is the perfect artistic accent and it's functional as well. The red under gold art gilt page edging is so beautiful. It's a joy to open this bible up to see that red tone appear - a red tone matched to the red text (wow!). And even the three double sided silk ribbons (two black, one red) match the overall design of the bible. The goatskin is ... amazing ... this is my first goatskin bible and I'll not go back to any other type of leather again. It is nicely floppy on the first day. The bible feels like it is fully broken in on the first day you open it. The leather has a nice (naturally) pebbly texture but also feels somewhat smooth and is edge sewn for years of use. The edge gilt on the inside of the cover is beautifully done and perfectly frames the text block when the bible lies open - which it does flawlessly. The spine of the bible lacks raised dividers instead having printed dividers. They do the job nicely and the dual thin gold lines at each location is a very nice artistic touch adding to the overall presentation of the finished product. Simple text on the spine tastefully complete the overall design: HOLY BIBLE ... New King James Version ... Thomas Nelson. Nothing else is needed. Things that are somewhat unimportant to me but should be mentioned in case these matter to you: the bible maps are nicely done and the sizable concordance is impressive (albeit the font is a bit small). Note I'm in my 60's now and I've noticed many of my old bibles (old, dear friends) seem to have shrinking text recently. Ah, 60's ... oh joy. That is what drove me to seek out bibles with the 2K/Denmark fonts. This has been such a delightful surprise. The bible is a complete invitation to read. I read it daily and wish I had more time to devote to it. This is, to date, the best bible I've ever owned at any price point. I gladly give this bible my highest recommendation.
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Reviewed in the United States on June 22, 2022

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