SKU: 22075748859

Sirtuin 1 Activator - 60 capsules

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Description

Sirtuin 1 Activator - 60 capsulesSwitch On the Longevity Gene Activates and supports SIRT1*1 7 Promotes healthy aging at the cellular level*2,3,8 11 Strengthens the bodys antioxidant network*12 Helps maintain metabolic and inflammatory health*13 Boosts mitochondrial biogenesis and energy output*1,3 View Certificate of Analysis The Science of SIRT1 Inside every cell is a guardian protein called sirtuin 1 (SIRT1), short for Silent Information Regulator. It helps decide which parts of

Switch On the Longevity Gene

  • Activates and supports SIRT1*1-7
  • Promotes healthy aging at the cellular level*2,3,8-11
  • Strengthens the body’s antioxidant network*12
  • Helps maintain metabolic and inflammatory health*13
  • Boosts mitochondrial biogenesis and energy output*1,3

View Certificate of Analysis

The Science of SIRT1

Inside every cell is a guardian protein called sirtuin 1 (SIRT1), short for Silent Information Regulator. It helps decide which parts of your DNA stay quiet and which stay active, helping cells adapt to stress, maintain energy efficiency, and resist the effects of aging.

Commonly known as the "longevity switch," SIRT1 is involved in DNA repair, the removal of damaged cellular components, and the optimization of energy use. As we age, SIRT1 activity naturally declines due to factors such as oxidative stress, poor diet, disrupted sleep, and environmental challenges. This reduction is linked to diminished cellular resilience and many of the classic signs of aging.

The good news is that certain food compounds can help support SIRT1 function. Plant-derived polyphenols such as resveratrol (from red grapes) and pterostilbene (from blueberries) are among the best-studied for their ability to activate SIRT1 and promote healthy cellular aging. These compounds mimic calorie restriction at the molecular level, helping to reactivate SIRT1 and restore youthful gene expression patterns. By boosting SIRT1 activity, they help shift cells into a protective, repair-focused state, supporting the body’s natural defenses as we age.*1-7

Why Resveratrol + Pterostilbene Work Better Together

Resveratrol is well-known for supporting SIRT1, but the body clears it fast. The liver converts most of it into inactive metabolites within minutes. Blood levels fall quickly, so only a limited amount reaches cells. The effect on SIRT1 is meaningful, yet short-lived.*1-3,5-7

Pterostilbene shifts the profile. It is a close relative of resveratrol with two methyl groups that improve its performance.

  • Up to 4× higher oral bioavailability*
  • Greater lipophilicity for superior cellular penetration*
  • Significantly longer half-life in the body (up to 7× longer than resveratrol)*4,14-16

When used together in a balanced ratio, the two ingredients work in sequence. Resveratrol supports a fast SIRT1 response. Pterostilbene keeps that response active for a longer period due to its greater stability. This provides steadier sirtuin pathway support than resveratrol alone.*1-7,14-16

What Makes Ours Better?

  • 4:1 Polyphenol Complex: Balanced to reflect bioavailability differences between resveratrol and pterostilbene.
  • Clinically Studied Forms: Includes the active trans form of resveratrol and pterostilbene for consistency and purity.
  • Longevity Pathway Support: Engages SIRT1, AMPK and PGC-1α pathways linked to mitochondrial function and cellular upkeep.*1-7
  • Minimalist Formula: Uses only active polyphenols for a straightforward, clean profile.*

The ProHealth Difference

  • Doctor-Formulated: Developed by our in-house science team in collaboration with leading wellness experts.
  • Triple Lab Tested: Verified three times by independent labs for purity and potency.
  • Full Transparency: Third-party test results published online for complete confidence.
  • USA Manufactured: Proudly manufactured in the USA in FDA-registered, GMP-certified facilities since 1988.
  • 100-Day Risk-Free Guarantee: If you’re not fully satisfied, we’ll refund your purchase in full.

A Word from our Chief Science Officer

"Resveratrol brought SIRT1 into the spotlight, but bioavailability has always limited its potential. By combining it with pterostilbene, we’re matching kinetics with biology — ensuring both rapid activation and sustained support of this key longevity pathway."

Ingredient Info

Trans-Resveratrol: The active, naturally occurring form of resveratrol that supports key cellular pathways involved in healthy aging.*
Trans-Pterostilbene: A lipophilic stilbene that engages the SIRT1 pathway and complements resveratrol for steady cellular support.*

References:

  1. Della Vedova L et al. Pharmaceuticals (Basel). 2025;18(2):138.
  2. Zhou DD et al. Subcell Biochem. 2024;107:183-203.
  3. Li YR et al. Biofactors. 2018;44(1):69-82.
  4. Wood JG et al. Nature. 2004;430(7000):686-689.
  5. Kuršvietienė L et al. Medicina. 2016;52(3),148-155.
  6. Lakshminarasimhan M et al. Aging (Albany NY). 2013;5(3),151.
  7. Borra MT et al. J Biol Chem. 2005;280(17),17187-17195.
  8. Thaung Zaw JJ et al. Clin Nutr. 2021;40(3):820-829.
  9. Thaung Zaw JJ et al. Menopause. 2021;28(1):40-49.
  10. Wong RH et al. J Bone Miner Res. 2020;35(11):2121-2131.
  11. Thaung Zaw JJ et al. Nutrients. 2020;12(3):828.
  12. Chan EWC et al. J Appl Pharm Sci. 2019;9(7):124-129.
  13. Della Vedova L et a. Pharmaceuticals (Basel). 2025;18(2):138.
  14. Wang P, Sang S. Biofactors. 2018;44(1):16-25.
  15. Riche DM et al.  J Toxicol. 2013;2013:463595.
  16. Kapetanovic IM et al. Cancer Chemother Pharmacol. 2011;68(3):593-601.
Supplement Facts
Serving Size: 1 Capsule
Servings Per Container: 60
Amount Per Serving %DV
Veri-te® Trans-Resveratrol 200 mg
Trans-Pterostilbene 50 mg
† Percent Daily Values (DV) not established

REV.10.25

Veri-te® is a registered trademark of the Lallemand group.
  • OTHER INGREDIENTS: Rice flour, hypromellose (capsule).
  • SUGGESTED DAILY USE: Take one (1) capsule per day with food.
  • CAUTION: For use by healthy adults only. Please consult your physician before use if you are pregnant or nursing, under the age of 18, or are undergoing treatment for a medical condition. Do not exceed the suggested use. KEEP OUT OF REACH OF CHILDREN. Store in a cool and dry place after opening.
Shipping Notes
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Exchange/Return Notes
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SKU: 22075748859

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Shani G.
Lake Worth, US
★★★★★ 5
Fit and quality
Color: Navy Blue, Size: Small
Very nice suits. Good quality and size is pretty spot on as long as you take measurements. I have bought this brand in two different colors for my son's high-school proms. Both suits held up well and were a good fit. He is tall and skinny. 6 ft and 135 lbs. Wears a 28/34 jeans lol. The small pants fit better for his waist and small jacket fit but he preffered the little closer fit of the medium size jacket. Overall very happy with purchase and would recommend for anyone looking for a cheap suit for a wedding or prom. Its affordable and they have many color options.
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Reviewed in the United States on May 8, 2026
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Trivia
Fort Morgan, US
★★★★★ 5
Profesionally Fit and Tailored outfit
Color: Black, Size: Large
Pretty professional and great outlook wearing it with a tie. Can be used in any environment but not in a warmth area with a Jacket. Feels pretty comfortable. Material was great indeed and pretty silky from the inside.
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Reviewed in the United States on May 26, 2026
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Daniel Customer
Louisville, US
★★★★★ 4
pretty good for the price
Color: Brilliant Black, Size: Large
pretty darn good for the price. You can tell its cheap when you feel it and look close but its really not bad. Surprisingly it fit very well. (for reference Im 6' 1.5" 180 pounds and everything fit me good, except the pants that were a little baggy and the vest a little short) but for the price its good. Its nice enough you can wear it out and not feel like your wearing a Halloween costume or something.
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Reviewed in the United States on November 14, 2025
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Gladys perez
Lowell, US
★★★★★ 5
Perfect for such a special occasion
Color: Brilliant Black, Size: Medium, Color: Brilliant Black, Size: Medium
I bought this suit for my son's graduation and was very satisfied. It looks elegant and modern, and the fit was excellent. The fabric is comfortable and of good quality—ideal for wearing for several hours. I received many compliments that day. Without a doubt, a very good choice for important and special events.
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Reviewed in the United States on May 16, 2026
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Jesse
Alexandria, US
★★★★★ 5
Feels Tailored, Perfect Fit, Fast Delivery, Zero Complaint
Color: Black, Size: Large
I honestly did not expect this level of quality ordering a suit online, especially on such short notice, but this completely exceeded my expectations. First off, the fit is incredible. The jacket feels like it was tailored specifically for me, it wraps cleanly around the shoulders and arms without being tight, and tapers perfectly at the waist. I still have full range of motion, which is rare for a fitted jacket. The one-button design gives it a modern, sleek look that really stands out. The pants are just as impressive. They fit perfectly, not too tight, not too loose, with a clean, straight fall that looks amazing with dress shoes. The length is spot on, and the overall structure makes it look very polished. I also appreciate the thoughtful details like secure closures, belt loops, and well-placed pockets. The vest was the cherry on top. It fits clean and adds an extra level of sophistication to the whole outfit. Together, the full set gives a very sharp, put-together look without feeling overdone. What really shocked me was the speed. I ordered this late at night and received it the next morning. That alone would have been impressive, but to combine that kind of delivery with this level of quality is next-level. Overall, this suit looks, feels, and fits far better than I expected at this price point. If you're hesitant about buying a suit online, this is definitely one of those rare cases where it absolutely pays off. Highly recommend.
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Reviewed in the United States on March 27, 2026

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