SKU: 64283036915

Essentials NMN 500 - Nexergy™ NMN - 500 mg, 30 capsules

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Description

Essentials NMN 500 - Nexergy™ NMN - 500 mg, 30 capsulesLaboratory Grade NMN Without the Premium Price* Restore NAD+. Reignite Cellular Energy.* Rapidly increases NAD+ levels to support cellular energy*17 Powers mitochondrial function for sustained vitality*35,7,8 Enhances daily energy at the cellular level*2,48 Supports DNA repair and cellular resilience*1,2,4,5,79 Helps counter age related cellular decline*16,8,9 View Certificate of Analysis Nexergy NMN capsules deliver 500 mg of pure NMN one of the most

Laboratory-Grade NMN — Without the Premium Price*

Restore NAD+. Reignite Cellular Energy.*

  • Rapidly increases NAD+ levels to support cellular energy*1–7
  • Powers mitochondrial function for sustained vitality*3–5,7,8
  • Enhances daily energy at the cellular level*2,4–8
  • Supports DNA repair and cellular resilience*1,2,4,5,7–9
  • Helps counter age-related cellular decline*1–6,8,9

View Certificate of Analysis

Nexergy™ NMN capsules deliver 500 mg of pure NMN — one of the most direct NAD+ precursors — in a simple, convenient daily dose backed by clinical research.

NAD+ is essential to how your cells produce energy, repair DNA, and maintain healthy function over time. But by midlife, levels can drop by up to 50% — impacting how you feel, perform, and age.

Feel more like yourself again with daily NAD⁺ restoration.

The Science Behind NAD+ Restoration

NAD+ (nicotinamide adenine dinucleotide) is a vital coenzyme found in every cell of your body, essential for converting nutrients into energy, activating DNA-repair enzymes (PARPs), and regulating sirtuins — proteins that influence gene expression and longevity. As a cornerstone of cellular metabolism, NAD+ supports energy production, DNA integrity, and healthy aging.*12-16

One of the most effective ways to maintain NAD+ is with Nicotinamide Mononucleotide (NMN) — a clinically studied form of vitamin B3 that supports the body’s natural NAD+ production pathways, helping you feel energized, resilient, and more youthful.*1,3,10-16

Essentials, featuring NexergyNMN: Laboratory-Grade NMN — Without the Premium Price

Nexergy™ NMN delivers the same NAD+-boosting molecule used in university longevity research — but without paying premium prices for branded clinical trials and luxury positioning.

Backed by triple lab testing and rigorous quality standards, it provides laboratory-grade NMN in a clean, convenient capsule at an everyday price point.

Superior Absorption. Better Utilization.

Unlike conventional crystalline NMN, which can be slower to dissolve and absorb, Nexergy™ NMN is engineered as an advanced amorphous form — designed to dissolve faster and more completely in your digestive system.*

This enhanced bioavailability helps your body extract and utilize more NMN per dose — potentially delivering comparable or greater biological effect at lower milligram amounts than standard formulations.*

Simply put: you get more NAD+ support from every dose.

What Makes Nexergy™ NMN Better

  • Advanced Amorphous Formulation: Unlike conventional crystalline NMN, our non-crystalline structure dissolves faster and more completely in your digestive system, enhancing bioavailability.*
  • Laboratory-Grade Science at Everyday Pricing: Delivers the same NMN molecule trusted in university longevity research — without the premium clinical trial markup.*
  • Efficient NAD+ Uptake: Enhanced absorption means your body extracts and utilizes more NMN per dose, potentially delivering comparable NAD+ support at lower milligram amounts than standard formulations.*
  • 500 mg Pure NMN: Clinically studied dosing to support rapid NAD+ restoration and cellular energy.*

Power Up Your Cells With NMN*

Nicotinamide Mononucleotide (NMN) is one of the most promising breakthroughs in longevity science. As a powerful vitamin B3 derivative and direct NAD+ precursor, it helps fuel the cellular energy, repair, and resilience needed to promote healthy, vibrant aging.*

Rebuild Your Body's NAD+ Supply — Daily*

To maintain peak performance, your body requires a steady supply of NAD+. With NMN, you can effortlessly and continuously support your NAD+ levels. Research demonstrates that supplementing with NMN can elevate NAD+ levels in a dose-dependent manner, meaning higher doses yield greater increases in NAD+ concentrations.*1,2,4-7,9

Fuel Cellular Energy Production*

NAD+ plays a vital role in converting food into usable energy at the cellular level. With NMN, you can optimize ATP production, leading to enhanced energy availability throughout the body. This boost in cellular energy not only supports physical performance but also contributes to enhanced quality of life.*2,4-8

Target All 12 Hallmarks of Aging*

As we age, NAD+ levels naturally decline, making replenishment essential to support core longevity processes. NAD+ targets the root causes of aging, fueling essential enzymes like PARPs, which repair DNA and maintain cellular integrity, and activating Sirtuins, which regulate gene expression, inflammation, and stress response — key contributors to healthy aging.*1-6,8,9

The ProHealth Difference

  • Triple Lab Tested: Rigorously tested three times by independent third-party labs to guarantee unmatched potency and purity.
  • Full Transparency: In an industry full of misleading claims, we publish our third-party lab results — so you always know exactly what’s in every bottle.  
  • Used in University Longevity Research: Nexergy™ NMN is the same laboratory-grade formulation trusted by leading longevity studies — now accessible at an everyday price point.
  • 100-Day Risk-Free Guarantee: We stand behind our products. If you’re not completely satisfied, contact our Santa Barbara, CA office for a full refund — no hassle, no questions asked.

Pioneering Longevity Since 1988

For over 38 years, ProHealth has been dedicated to crafting the world's highest-quality supplements — rooted in innovation, integrity, and a passion for healthy aging. With a long-standing A+ rating from the Better Business Bureau, our reputation for purity and potency has made us one of the most trusted names in the industry. Our commitment to scientific rigor, premium sourcing, and results you can feel continues to drive everything we do.

Invest in the Long Game

Your cells are counting on NAD+.

Get research-grade NMN without the premium markup — order Nexergy™ NMN today and start feeling the difference.

Ingredient Info

Nexergy™ Nicotinamide Mononucleotide (NMN) 500 mg: A vitamin B3 derivative and essential precursor in the NAD+ production pathway.*

References:

    1. Yi L, et al. GeroScience. 2023;45(1):29–43.
    2. Yamane T, et al. Clin Nutr ESPEN. 2023;56:83–86.
    3. Igarashi M, et al. NPJ Aging. 2022;8(1):5.
    4. Okabe K, et al. Front Nutr. 2022;9:86864
    5. Kim M, et al. Nutrients. 2022;14(4):755.
    6. Irie J, et al. Endocr J. 2020;67(2):153–160.
    7. Liao B, et al. J Int Soc Sports Nutr. 2021;18(1):54.
    8. Janssens GE, et al. Nat Aging. 2022;2(3):254–263.
    9. Katayoshi T, et al. Sci Rep. 2023;13(1):2786.
    10. Huang H. Front Aging. 2022;3:851698.
    11. Yamaguchi S, et al. Endocr J. 2024;71(2):153–169.
    12. Orr ME, et al. GeroScience. 2024;46(1):665–682.
    13. Nascimento EBM, et al. J Clin Endocrinol Metab. 2021;106(5):1437–1447.
    14. Vreones M, et al. Aging Cell. 2023;22(1):e13754.
    15. Elhassan YS, et al. Cell Rep. 2019;28(7):1717–1728.e6.
    16. Martens CR, et al. Nat Commun. 2018;9(1):1286..
Supplement Facts
Serving Size: 1 Capsule
Servings Per Container: 30
Amount Per Serving %DV
Nexergy™ NMN
  (Nicotinamide Mononucleotide)
500 mg
† Daily Value (DV) not established.
REV.01.26 
Nexergy™ is a trademark of ProHealth, Inc.

  • OTHER INGREDIENTS: Hypromellose (capsule), rice flour.
  • SUGGESTED DAILY USE: Take one (1) capsule, 1-2 times per day, with or without food, preferably in the morning.
  • CAUTION: Please consult your physician before use if you are pregnant or nursing, under the age of 18, or are undergoing treatment for a medical condition. Do not exceed the suggested use. KEEP OUT OF REACH OF CHILDREN. Store in a cool and dry place.
Shipping Notes
  • Free Standard Shipping on $100+ Orders to the USA.
  • Except Preorder products are shipped in 48 hours.
  • Delivery to the USA:
  1. Standard Shipping : 3-10 business days
  • If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
  • Please click here for more details>>> Return & Exchange Policy
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4.3 ★★★★★
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Matthew Paul
Whiting, US
★★★★★ 4
Perfect for Our Nervous Rescue Dog
Size: Large, Color: Green
First Impressions I bought the Pupsicle for our new rescue dog who was very nervous whenever we had to leave the house. Right out of the box it felt sturdy and well-made, and I liked that it wasn’t just another cheap chew toy. ⸻ Setup & Ease of Use I went with the premade treat inserts to start, which made it super simple — just pop one in and hand it over. It’s also dishwasher-safe, which is a huge win for me since I don’t want to deal with scrubbing peanut butter out of toys. ⸻ Performance in Real Life She loves it. The Pupsicle has kept her occupied and calm, which has really helped her acclimate to her new home. Instead of pacing or whining when we leave, she settles down with this toy and stays busy. ⸻ Pros & Cons Pros: • Helps reduce anxiety for nervous dogs • Very durable and solid • Easy to clean (dishwasher safe) • Premade inserts make it effortless Cons: • On the heavier side, so probably best for medium+ dogs • Inserts are convenient but add a little extra cost ⸻ Who It’s For Perfect for new dog owners, rescues, or anyone with a dog who needs a healthy distraction when left alone. ⸻ Final Verdict The Pupsicle has made a noticeable difference for our rescue pup. It’s durable, easy to use, and has genuinely helped her feel more at ease in her new environment. Highly recommend.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on August 24, 2025
T
Verified Purchase
taximom
Dallas, US
★★★★★ 3
Dogs love it, hard to open and close
Size: Large, Color: Pink, Size: Large, Color: Pink
My dogs love this toy. It keeps them entertained a long time. Great calming toy for when you leave the house. Only issues is it is very hard to open and close. One of mine I had three people try to open and after fighting with it for about an hour I finally got it opened. Got 2, one a blue and pink one for each of my dogs. The blue is easier than the pink but still hard to do. Just not as bad. Can't close the pink all the way because it is so hard to close. The dog that uses it has trouble getting the stuff out of it. But it doesn't stop her from trying for hours to do so. Does get some teeth marks on it as well if they are aggressive chewer. Tried multiple eatable lubricating substances to try to make it easier but so far nothing fully worked. Aloe Vera has worked the best so far, but not great.
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Reviewed in the United States on February 17, 2026
C
Verified Purchase
CS Niles
Birmingham, US
★★★★★ 3
Good in theory, but didn’t fully deliver
Size: Large, Color: Green, Size: Large, Color: Green
My dog falls right on the size cutoff between the small and large Pupsicle. I initially ordered the large since he’s a strong chewer, but he had trouble getting everything out, so I ended up trying the small as well. There are definitely some positives. I think the design is better than a Kong. It stays upright, which makes it less messy. I also really like the mold for making the inserts, instead of having to fill the toy itself and freeze it. That said, there are two major design issues that impacted my experience. First, the all-rubber construction creates a lot of friction when screwing the bottom into the base, especially after repeated use. It gradually became harder to open, to the point where I was using coconut or avocado oil to try to loosen the threads. At one point I even needed a wrench and pliers just to get a better grip. Second, while it’s marketed as dishwasher safe (which I was excited about for cleaning), it seems to dry out the rubber and makes the threading issue worse over time. Unfortunately, mine is now permanently stuck shut and no longer usable. Overall, I like the concept, but the durability and usability issues make this a 3-star product for me. I’d recommend it with caution, especially if you plan to wash it frequently.
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Reviewed in the United States on April 23, 2026
K
Verified Purchase
Klara Gengler
Houston, US
★★★★★ 5
Last a while. Will be buying more toys soon.
Color: Consuela the Cactus - Large, Size: Large Dog
Best dog toy I have ever bought. I have three dogs, two at the time I bought this toy. It took them over a year to break through the first layer. The flower comes off first so be careful your dog doesn't swallow it. It still has the second layer so it still looks like a cactus. No stuffing to clean up when they tear into it, which makes it far less messy than other toys. One of my dogs is obsessed with fetch so I use it like a ball inside. The oval shape makes it hard to ensure when it bounces that it will bounce straight. It's bounced into walls and other stuff that I wasn't intending it to hit. Not much of a squeak so I can let them play with it for hours and I don't get annoyed with the noise. Great toy that lasts a while.
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Reviewed in the United States on September 25, 2025
C
Verified Purchase
Cassie
New York, US
★★★★★ 5
Nice Value
Color: Consuela the Cactus - Large, Size: Large Dog
Very cute! Its soft and feels like it is well made. It is a heavier toy and a tougher one. Not a plush toy. I will order again for our older dogs. Nice value for sure!
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Reviewed in the United States on June 11, 2026

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