SKU: 62180059624

Biotin Rat Anti-Mouse F4/80 Antibody (S-R537)

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Description

Biotin Rat Anti-Mouse F4/80 Antibody (S-R537)Product Specification Host Rat Antigen F4 80 Synonyms Adhesion G protein coupled receptor E1; Cell surface glycoprotein F4 80; EGF like module receptor 1; EGF like module containing mucin like hormone receptor like 1; EMR1 hormone receptor; Emr1; Gpf480; Adgre1 Location Cell membrane Accession Q61549 Clone Number S R537 Antibody Type Rat mAb Isotype IgG2a,k Application FCM Reactivity Ms Positive Sample BALB c mouse peritoneal exudates cells

Product Specification


Host Rat
Antigen F4/80
Synonyms Adhesion G protein-coupled receptor E1; Cell surface glycoprotein F4/80; EGF-like module receptor 1; EGF-like module-containing mucin-like hormone receptor-like 1; EMR1 hormone receptor; Emr1; Gpf480; Adgre1
Location Cell membrane
Accession Q61549
Clone Number S-R537
Antibody Type Rat mAb
Isotype IgG2a,k
Application FCM
Reactivity Ms
Positive Sample BALB/c mouse peritoneal exudates cells
Purification Protein G
Concentration 0.2 mg/ml
Conjugation Biotin
Physical Appearance Liquid
Storage Buffer

PBS, 0.3% Proclin 300
Stability & Storage 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.

Dilution


application dilution species
FCM 5μl per million cells in 100μl volume Ms

Background

F4/80, also known as ADGRE1 or EMR1, is a cell surface glycoprotein and a member of the EGF-TM7 protein family. It is widely used as a marker for mature mouse macrophages and is highly expressed in various macrophage populations, such as Kupffer cells in the liver, Langerhans cells in the skin, and microglial cells in the brain. However, its expression in human cells is different, being mainly found in eosinophils and some macrophages. F4/80 is an orphan receptor involved in cell adhesion and immune cell interactions, and it may also play a role in the development of regulatory T cells. The protein has a large extracellular domain containing multiple EGF-like calcium-binding domains, linked to a seven-transmembrane domain characteristic of G protein-coupled receptors.

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SKU: 62180059624

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4.2 ★★★★★
Based on 29 reviews
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Product Reviews
H
Happy Face
Dallas, US
★★★★★ 5
Duck-time is play-time! Exactly what a dog toy should be!
Duck hunting for your living-room princess-pal best buddy goodest puppy in the world! Every dog deserves a chance to be a heroic duck hunting hero! This dog toy is a favorite of my pup. Duck-time is play time! This duck is made with several fabulous textures. There's a ropey texture around the neck, a burlap type texture for the body and head, and a felt-like texture for the bill and feet. My dog immediately tore the feet off! He always removes any hanging bits from all toys, so that's not a comment to the detriment of this product. He's working on the wings, now. My dog likes to chase this toy when I throw it or play tug-of-war with it, or is willing to sit and chomp on it by himself for a while. The rope is intact, still! This is exactly what a dog toy should be! Give your little buddy a hunting trophy!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on November 2, 2025
B
Buyerone
Phoenix, US
★★★★★ 2
Speaker broken
This toy is advertised as having a squeaker, but the one we had was defective and did not make any noise. Our dog still throughly enjoyed ripping this little duck to shreds through. The material was thicker than I was expecting but still only took our dog about 5 mins to completely destroy it (Golden retriever). I understand that this toy is marketed as for small dogs so I get that, but took away three starts because our came with the broken squeaker and for $10, you can find a lot better toys at TJ Max. This item is not a good value for our experience.
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Reviewed in the United States on November 1, 2025
A
Amazon Vine Reviewer
West Palm Beach, US
★★★★★ 5
Durable duck toy for man’s best friend
Although it was suggested that this toy would be best for small breeds, I found that it’s durable enough for my 80 pound Irish setter! It has literally become his best friend. He takes it everywhere he goes! There’s a small squeaky noise that comes from the neck area that he has to work to find. I’m sure he will eventually destroy this as he has with all his other toys, but it’s really holding up much better than anticipated. It is well worth the $10 cost.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on November 9, 2025
T
Ted and Katie
Chelsea, US
★★★★★ 5
Really cute, well made dog toy. Was a huge hit with our pup
This toy was a big hit! Pros - love the heavy duty burlap-kinda fabric. Our new puppy has razor sharp teeth but this fabric is holding up really well. - size is great for a variety of breeds - shape is perfect for grabbing onto. Our puppy especially likes picking it up on the neck where the toy is more slender - the extra little feet and wing flaps add some interest that have really kept her occupied Cons - the squeaker is in the neck where the fabric has embellishments and is a little thicker. It's a little hard to activate the squeaker but maybe the toy/stuffing needs to get broken in more and then it will be easier to squeeze that section
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Reviewed in the United States on October 29, 2025
C
Verified Purchase
csboyd
Charlottesville, US
★★★★★ 5
A must have for active dogs
Size: Max Size, Size: Max Size
I normally do not write reviews unless a product is really good or really bad. I have a dog that thinks chasing balls is the only thing in life and unfortunately she has a mom that has anchor pins in both shoulders. We've been using this ball launcher for little over a year. It goes through about 32 dirty balls, 3 times a day and has held up amazingly. It is even full of dirt and still keeps on working, it looks like R2D2 went thru a battle. 😆 I recently bought a second one as a back up because I can't believe this poor thing hasn't given up yet. I rotate the balls because my dog brings them back wet and muddy, then they won't launch as far, so I knock some dirt off of a dry one and launch it. I would highly recommend this for active dogs.
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Reviewed in the United States on May 25, 2026

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