SKU: 37993503236

TEAD1 Protein, Human

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Description

TEAD1 Protein, HumanProduct Specification Species Human Synonyms TEAD1, NTEF 1, Protein GT IIC, TEA domain family member 1, Transcription factor 13, TCF 13 Accession P28347 Amino Acid Sequence SUMO Arg209 Asp426 Expression System E. coli Molecular Weight 28kDa Purity >95% by SDS PAGE Endotoxin <1EU g Conjugation Unconjugated Tag No Tag Physical Appearance Lyophilized Powder Storage Buffer 20mM Tris, 150mM NaCl, 1mM DTT, pH8. 0 Reconstitution Reconstitute at 0. 1 1 mg ml

Product Specification


Species Human
Synonyms TEAD1, NTEF-1, Protein GT-IIC, TEA domain family member 1, Transcription factor 13, TCF-13
Accession P28347
Amino Acid Sequence SUMO-Arg209-Asp426
Expression System E.coli
Molecular Weight 28kDa
Purity >95% by SDS-PAGE
Endotoxin <1EU/μg
Conjugation Unconjugated
Tag No Tag
Physical Appearance Lyophilized Powder
Storage Buffer 20mM Tris, 150mM NaCl, 1mM DTT, pH8.0
Reconstitution Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

1、Zhou Y. et al. (2017) TEAD1/4 exerts oncogenic role and is negatively regulated by miR-4269 in gastric tumorigenesis. Oncogene. 257: 1-13.

Background

TEA domain (TEAD) transcription factors are key components of the Hippo-YAP1 signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. Dysregulation of the Hippo pathway leads to the activation of YAP1 and further culminates in the development of multiple human cancers. Moreover, YAP1 interacted with TEAD1, exerted their transcriptional control of the functional target, glucose transporter 1 (Glut1). Overexpression of Glut1 restored the inhibitory effects of YAP1 knockdown on glycolysis as demonstrated by glucose consumption and lactate production. TEAD1 and TEAD4 are oncogenic factors, whose aberrant activation are, in part, mediated by the silence of miR-377-3p, miR-1343-3p and miR-4269.

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SKU: 37993503236

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4.2 ★★★★★
Based on 6 reviews
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Product Reviews
K
Verified Purchase
Keeli
Carnegie, US
★★★★★ 5
Perfect for small senior dogs!
Size: Extra Small (Pack of 1), Color: Pink
So I actually bought this for my senior Bolonka. She has a neurological disorder that does not allow her to have hard bones or treats, plus I am trying to protect her teeth for as long as I can. This is a GREAT toy. I like to fill up the middle with yogurt or peanut butter and things she can lick instead of bite into. This is the PERFECT size for her. She likes to play with it even without a treat on the inside. She just carries it around the house , as its not heavy at all, and throws it around, it is too cute! It is not loud at all, the only noise that comes out is if shes got a ton of saliva and her teeth rub against it. I just pulled it off the packaging, washed it, and it was ready to go. It will last forever with my baby because she doesn't chew hard so I am unsure about the durability for bigger pups or dogs who are heavy chewers. I am so glad I got this for her and I would HIGHLY recommend it!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 13, 2026
K
Verified Purchase
Kindle Customer
Pawtucket, US
★★★★★ 5
Good quality
Size: Small (Pack of 1), Color: Blue
Bought this as an upgrade for my dog's Kong that she got as a puppy and it's just as good as the smaller one. It works really goodBought this as an upgrade for my dog's Kong that she got as a puppy and it's just as good as the smaller one. It works really good
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Reviewed in the United States on June 3, 2026
S
Verified Purchase
Samantha
Waukegan, US
★★★★★ 4
Good product misleading size.
Size: Small (Pack of 1), Color: Blue
Really disappointed about the size. It is way too small for my berniedoodle. He still likes it for play but I’m afraid he might swallow it. It’s very sturdy tho and is chew resistant. I guess I didn’t pay attention to the size. Looked big in the picture.
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Reviewed in the United States on April 18, 2026
J
Verified Purchase
Jess M
Fort Morgan, US
★★★★★ 5
Must have item for dogs!!!
Size: Medium (Pack of 1), Color: Pink
The puppy kong is a must have item for every new puppy owner. Super cute!! They usually will last forever (unless you have a super chewer then you need the black one). Great value!! Keeps the puppy busy and entertained. Especially when frozen. Google and the Kong website have tons of recipes. I tend to stick with a little bit of kibble some mashed banana and peanut butter. Also, good options are jars or pouches of baby food just make sure you check the label to ensure there is nothing toxic to dogs in it. More options are kibble soaked in water or broth, pumpkin puree, green beans and carrots. I could go on forever. If you own a dog, a Kong is a must have! I always have two ready to go. And they are dishwasher safe!
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Reviewed in the United States on January 19, 2026
B
Verified Purchase
Bill
Belleville, US
★★★★★ 5
Keeps her occupied!
Size: Extra Small (Pack of 1), Color: Pink
It works very well when sruffed with a healthy, soft treat. It keeps our little teething scamp busy for a while and stops her from chewing on household items including her humans!
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Reviewed in the United States on May 10, 2026

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