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Description
Phospho-Glycogen Synthase (Ser641) Recombinant Rabbit mAb (S-2765-18)Product Specification Host Rabbit Antigen Phospho Glycogen Synthase (Ser641) Synonyms Glycogen [starch] synthase, muscle; Glycogen synthase 1; GYS; GYS1 Immunogen Synthetic Peptide Location Cytoplasm Accession P13807 Clone Number S 2765 18 Antibody Type Recombinant mAb Isotype IgG Application WB Reactivity Hu, Ms, Rt Positive Sample HeLa, NIH 3T3, PC 12 Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid
Product Specification
| Host | Rabbit |
| Antigen | Phospho-Glycogen Synthase (Ser641) |
| Synonyms | Glycogen [starch] synthase, muscle; Glycogen synthase 1; GYS; GYS1 |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm |
| Accession | P13807 |
| Clone Number | S-2765-18 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB |
| Reactivity | Hu, Ms, Rt |
| Positive Sample | HeLa, NIH/3T3, PC-12 |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000-1:5000 | Hu, Ms, Rt |
Background
Phospho-Glycogen Synthase (Ser641) is the inactive, phosphorylated form of glycogen synthase in which a phosphate group is covalently attached to serine-641; this single modification, catalyzed chiefly by glycogen synthase kinase-3 (GSK-3) downstream of insulin signaling, sterically hinders the enzyme’s active site and prevents the elongation of glycogen chains, thereby providing a rapid, reversible switch that links hormonal cues to systemic glucose storage.
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