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Description
FGL2 His Tag Protein, MouseProduct Specification Species Mouse Synonyms FGL2, T49, pT49 Accession P12804 Amino Acid Sequence Pro197 Pro432, with C terminal 8*His PVQHLIYKDCSDHYVLGRRSSGAYRVTPDHRNSSFEVYCDMETMGGGWTVLQARLDGSTNFTREWKDYKAGFGNLEREFWLGNDKIHLLTKSKEMILRIDLEDFNGLTLYALYDQFYVANEFLKYRLHIGNYNGTAGDALRFSRHYNHDLRFFTTPDRDNDRYPSGNCGLYYSSGWWFDSCLSANLNGKYYHQKYKGVRNGIFWGTWPGINQAQPGGYKSSFKQAKMMIRPKNFKPGGGSHHHHHHHH Expression System HEK293 Molecular Weight 38 43kDa Purity >95% by SDS
Product Specification
| Species | Mouse |
| Synonyms | FGL2, T49, pT49 |
| Accession | P12804 |
| Amino Acid Sequence | Pro197-Pro432, with C-terminal 8*His PVQHLIYKDCSDHYVLGRRSSGAYRVTPDHRNSSFEVYCDMETMGGGWTVLQARLDGSTNFTREWKDYKAGFGNLEREFWLGNDKIHLLTKSKEMILRIDLEDFNGLTLYALYDQFYVANEFLKYRLHIGNYNGTAGDALRFSRHYNHDLRFFTTPDRDNDRYPSGNCGLYYSSGWWFDSCLSANLNGKYYHQKYKGVRNGIFWGTWPGINQAQPGGYKSSFKQAKMMIRPKNFKPGGGSHHHHHHHH |
| Expression System | HEK293 |
| Molecular Weight | 38-43kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference |
1、Feng Y. et al. (2020) Fibrinogen-Like Protein 2 (FGL2) is a Novel Biomarker for Clinical Prediction of Human Breast Cancer. Med Sci Monit. 26: e923531. 2、Hou X X. et al. (2021) Regulatory T cells induce polarization of pro-repair macrophages by secreting sFGL2 into the endometriotic milieu. Commun Biol. 4(1): 499. |
Background
Fibrinogen-like protein 2 (FGL2) is a member of the fibrinogen-like protein family and possesses important regulatory functions in both innate and adaptive immune responses. Fibrinogen-like protein 2 (FGL2) exists in both soluble and membrane forms. Soluble fibrinogen-like protein 2 (sFGL2) has been recently identified as a novel effector molecule of Tregs and plays a pivotal role in regulating both innate and adaptive immunity. FGL2 mediates its immunosuppressive activity by binding to inhibitory FcγRIIB (CD32B) receptors expressed by antigen presenting cells (APC), including dendritic cells (DC) and B cells, and thus sFGL2 may inhibit the maturation of DC, resulting in the suppression of effector T cell responses and inducing apoptosis of B cells. However, nothing is known about sFGL2 and its potential roles in endometriosis.
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4.4 ★★★★★
Based on 23 reviews
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Product Reviews
★★★★★ 5
Perfect top
Size: Large, Color: Flamingo Pink
This sports bra is so comfortable and gives the right amount of support. The color is the same as photographed. This top pairs nicely with their leggings. Good quality for what you pay. True to size, will order in other colors!
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Reviewed in the United States on August 10, 2025
★★★★★ 5
Love it
Size: X-Small, Color: Slate Grey
Absolutely love this and the matching shorts. I wore the set to a spin class where you sweat a lot and found it to be very breathable and moisture-wicking.
The sports bra is very soft and true to size. I like the slate grey color a lot.
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Reviewed in the United States on July 29, 2025
★★★★★ 5
Amazon essentials products Good quality
Size: X-Small, Color: Flamingo Pink, Size: X-Small, Color: Flamingo Pink
The quality is excellent. It’s really gorgeous and fit. Perfect. I love Amazon essentials products
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Reviewed in the United States on December 12, 2025
★★★★★ 5
Soft and comfortable
Size: Medium, Color: Ocean Blue
I was really surprised how good it fits. I would say nothing about support with my A-cup but it definitely comfortable for everyday life and yoga. Good quality, absolutely value for its money. Will buy again.
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Reviewed in the United States on January 20, 2026
★★★★★ 5
Quality Material, Comfortable Fit
Size: Medium, Color: Emerald Green, Size: Medium, Color: Emerald Green
I often have trouble with sports bra bands feeling too constricting (for size 34C), but this one was comfortable enough to wear right away and I can tell it will get comfier as I wear it. I am 5’7, 130 lbs and bought a medium. The color is vibrant and the material feels high quality. Straps are not adjustable but that hasn’t been a problem up to this point.
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Reviewed in the United States on July 31, 2025