SKU: 69910434895

Rat Anti-Mouse Ly6C Antibody (S-4036)

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Description

Rat Anti-Mouse Ly6C Antibody (S-4036)Product Specification Host Rat Antigen Ly 6C Synonyms Lymphocyte antigen 6C1; Ly 6C1; Ly6c1 Location Cell membrane Accession P0CW02 Clone Number S 4036 Antibody Type Rat mAb Isotype IgG2a Application FCM Reactivity Ms Positive Sample C57BL 6 mouse bone marrow Purification Protein G Concentration 2 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS pH7. 4 Stability & Storage 12 months from date of receipt reconstitution, 2 to

Product Specification


Host Rat
Antigen Ly-6C
Synonyms Lymphocyte antigen 6C1; Ly-6C1; Ly6c1
Location Cell membrane
Accession P0CW02
Clone Number S-4036
Antibody Type Rat mAb
Isotype IgG2a
Application FCM
Reactivity Ms
Positive Sample C57BL/6 mouse bone marrow
Purification Protein G
Concentration 2 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS pH7.4
Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 1:200 Ms

Background

Ly-6C is a glycosylphosphatidylinositol-anchored cell-surface protein belonging to the Ly-6/uPAR/α-neurotoxin superfamily, selectively expressed on murine monocyte and T-cell subsets where it serves as a dynamic lineage and activation marker—its high level on pro-inflammatory “classical” monocytes (CD11b⁺Ly-6C^hi) enables their recruitment via CCR2 to inflamed tissues, whereas Ly-6C^lo monocytes patrol vasculature and replenish resident macrophages, and transient up-regulation on CD8⁺ T cells correlates with effector differentiation; structurally it forms a three-finger α-helical bundle that can laterally associate with lipid rafts and signaling partners such as T-cell receptor or integrin complexes to modulate calcium flux, cytokine release, and adhesion, thereby critically steering innate–adaptive immune crosstalk in infections, autoimmunity, and cardiovascular disease.

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Exchange/Return Notes
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SKU: 69910434895

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4.8 ★★★★★
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ChillyNilly
New York, US
★★★★★ 5
Perfect for sensory sensitive kids and for the pure beauty of it
Size: 2' x 6' (Natural), Color: Natural (Yellow Undertones), Size: 2' x 6' (Natural), Color: Natural (Yellow Undertones)
After speaking over the phone with the seller, I was confident in this purchase for my SPD son. They do not use harsh chemicals or dyes in the process. It is from New Zealand and the only use in Vietnam is for shipping. My son hasn't been diagnosed yet for Autism but he is in the process. He is super sensitive to all things sensory and Amazon feedback isn't the place to give specific details on his condition but I will write that when he fist touched it- which was willingly- he smiled and asked to sleep on it. When he laid down on it and I covered him- he was calm and smiling. In the pic I provided he is calm and holding his door (his obsession is doors and windows). He even set his door down to hold the fur. For other mommies and papas with spd/autistic kids you know that willingly touching a new fabric and setting down an obsessive item is huge and super encouraging! I am so grateful to have such a quality item that is affordable for my special needs son. His older sister received one as well as is now pretending to be a sheep. Fun for everyone! The ONLY negative is that the brand/info sticker on the pelt was a pain to get off and pulled some of the felt - not damaging it but blemishing the unity -but if the skin is down it will not be noticeable. A super fun detail is that all of the fur is combed out but there were a few strands that were wavy and had a slight curl- I LOVED that. There was no odor at all which is great! I expected an animal smell which is better than chlorine or dioxin which is what competitors use in their process. There is no noticeable seam in the middle on the top where the two pelts are gathered. I am soooo satisfied!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 13, 2016
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Verified Purchase
Sreitter1
Whiting, US
★★★★★ 5
Exactly as described and what I needed.
Size: 2' x 6' (Natural), Color: Wolf Tipped
I have a bad back along with other medical problems. I bought this for padding in my wheelchair. Very thick, soft, flexible, everything I needed. No smell and very little shedding even initially. Arrived quickly and well packaged.
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Reviewed in the United States on January 24, 2026
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Verified Purchase
DMB
Bozeman, US
★★★★★ 5
Great valur
Size: 2' x 3' (Natural), Color: Gray Tipped
Soft and comfortable. Quality leather nsckrd. Genuine sheepskin. No off odors. I'm skinny and not on tailbone. Hoping this helps. The grey tipped is more of a bluish gray. Pretty but not s true gray.
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Reviewed in the United States on March 31, 2026
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Verified Purchase
Outdoor Girl
Chelsea, US
★★★★★ 5
On the fence? This is the sheepskin to get!
Size: 2' x 3' (Natural), Color: Wolf Tipped
I've been reading all the reviews for sheepskins on AMZ and felt this company was the one to go for and WOW did they deliver! The sheepskin came well wrapped but not vacuum packed and is even prettier in person than the pictures. It is super soft, fluffy and dense and mine measured 26" x 40". I absolutely love the wolf tipped colors: ivory, dark grey and a slight brownish hue. There is a slight odor but I don't find it offensive. It stayed put on my leather couch and sitting on it during a Netflix movie was heavenly warm and comfortable. I did not observe any shedding. Will definitely buy another wolf tipped one, once it becomes available as it is worth the money.
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Reviewed in the United States on January 14, 2026
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Verified Purchase
The Marsh’s
Battle Creek, US
★★★★★ 5
Gorgeous 😍
Size: 2' x 6' (Natural), Color: Champagne, Size: 2' x 6' (Natural), Color: Champagne
Absolutely beautiful!!! It is thick and luxurious, super soft and cozy. It’s really high quality and it shows. You can tell it’s natural without the burn test even from its cute little curls. All brushed (your pet brush is perfect 😉) out it looks stunning and fluffy. I got the champagne color and I love it! I don’t see any seams on the double pelt and it is substantial, not at all like it will disintegrate in a few years, but rather will become a much loved family heirloom. Well worth the investment! It is absolutely heavenly to perform yoga on by the fire 😌I love taking my slippers off and feeling the soft fur. I don’t want to get off it lol. I understand all those other customer’s kids and cats 🤣😂🤣
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Reviewed in the United States on November 26, 2023

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